SCHEMBL28326258

SCHEMBL28326258

C=CN1C(=O)c2ccccc2C1=O.[KH]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
CASP3 P42574 2/20 0.46
POLB P06746 2/20 0.41
NPSR1 Q6W5P4 1/20 0.40
CYP1A2 P05177 1/20 0.39
EHMT2 Q96KQ7 1/20 0.39
EHMT1 Q9H9B1 1/20 0.39
CA12 O43570 2/20 0.38
CA9 Q16790 2/20 0.38
CA2 P00918 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
GLS O94925 1/20 0.38
CDC25B P30305 1/20 0.38
MAPT P10636 1/20 0.37
PKM P14618 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
MC4R P32245 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35297 0.98 ALDH1A1 (0.48) ALDH1A1CASP3POLBNPSR1CYP1A2
SCHEMBL30124938 0.98 ALDH1A1 (0.48) ALDH1A1CASP3POLBNPSR1CYP1A2
SCHEMBL29372938 0.98 ALDH1A1 (0.48) ALDH1A1CASP3POLBNPSR1CYP1A2
Allylamine SCHEMBL10531905 0.86 ALDH1A1 (0.49) ALDH1A1CASP3POLBNPSR1CA12
SCHEMBL14050320 0.85 ALDH1A1 (0.43) ALDH1A1CASP3POLBNPSR1CYP1A2
Succinimide SCHEMBL11137097 0.82 CRBN (0.46) ALDH1A1CASP3CYP1A2
Malonic Acid SCHEMBL30496168 0.82 CA12 (0.50) ALDH1A1CASP3POLBNPSR1CA12
SCHEMBL11937088 0.80 GSTP1 (0.36) ALDH1A1CASP3POLBCYP1A2CA12
SCHEMBL7619242 0.80 ALDH1A1 (0.44) ALDH1A1CASP3POLBNPSR1CA12
Benzenesulfonamide SCHEMBL15232899 0.80 CA2 (0.54) ALDH1A1CASP3CA12CA9CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110343196-A A kind of method and application based on ATRP living polymerization synthesis diamine base terminated polystyrene 西南石油大学 2019-10-18 CN disclosed