Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.86 |
| ▸ | RAB9A | P51151 | 6/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.86 |
| ▸ | SREBF2 | Q12772 | 3/20 | 0.86 |
| ▸ | NPC1 | O15118 | 2/20 | 0.86 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.62 |
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | AR | P10275 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ATP4A | P20648 | 2/20 | 0.56 |
| ▸ | ATP4B | P51164 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4282727 | 0.93 | KDM4E (1.00) | KDM4ERAB9ASMN1; SMN2SREBF2NPC1 | |
| SCHEMBL4280995 | 0.93 | SREBF2 (1.00) | KDM4ERAB9ASMN1; SMN2SREBF2NPC1 | |
| SCHEMBL14081497 | 0.93 | SREBF2 (1.00) | KDM4ERAB9ASMN1; SMN2SREBF2NPC1 | |
| SCHEMBL28522859 | 0.91 | RAB9A (0.73) | KDM4ERAB9ASMN1; SMN2SREBF2NPC1 | |
| SCHEMBL7532567 | 0.91 | RAB9A (0.73) | KDM4ERAB9ASMN1; SMN2SREBF2NPC1 | |
| SCHEMBL28534175 | 0.88 | KDM4E (0.75) | KDM4ERAB9ASMN1; SMN2SREBF2NPC1 | |
| SCHEMBL12601787 | 0.87 | RAB9A (0.75) | KDM4ERAB9ASMN1; SMN2SREBF2NPC1 | |
| SCHEMBL15160564 | 0.87 | KDM4E (0.71) | KDM4ERAB9ASMN1; SMN2SREBF2NPC1 | |
| SCHEMBL7217101 | 0.85 | KDM4E (0.78) | KDM4ERAB9ASMN1; SMN2SREBF2NPC1 | |
| SCHEMBL14315462 | 0.85 | LTA4H (0.66) | KDM4ERAB9ASMN1; SMN2SREBF2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204507-B | Process for producing 2-aryl-4-alkylthiazole compound | 浙江大学 | 2021-03-02 | — | — | CN | disclosed |
| CN-110204507-A | The preparation method of 2- aryl -4- hydrocarbyl thiazole compound | 浙江大学 | 2019-09-06 | — | — | CN | disclosed |