Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5491908 | 0.83 | AKR1C3 (0.46) | NR3C2NPSR1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL27911323 | 0.80 | KMT2A (0.50) | NR3C2SMN1; SMN2L3MBTL1TDP1RAB9A | |
| SCHEMBL15999740 | 0.77 | NR3C2 (0.49) | NR3C2NPSR1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL27541993 | 0.77 | NR3C2 (0.49) | NR3C2NPSR1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL27894063 | 0.77 | TSHR (0.54) | SMN1; SMN2RAB9AHTTKMT2APOLB | |
| SCHEMBL29206881 | 0.76 | CTSS (0.35) | NPSR1SMN1; SMN2RAB9AHTTKMT2A | |
| SCHEMBL1003807 | 0.75 | NPSR1 (0.61) | NR3C2NPSR1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL27617215 | 0.74 | AKR1C3 (0.47) | NPSR1SMN1; SMN2L3MBTL1TDP1RAB9A | |
| SCHEMBL31393783 | 0.73 | NPSR1 (0.45) | NR3C2NPSR1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL9068711 | 0.73 | PTPN1 (0.49) | NPSR1ALDH1A1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110183394-A | A kind of method that 3- nitrile ethyl -2- alkyl -4H- benzoxazine is prepared by bromoacetonitrile under the conditions of blue light illumination | 常州大学 | 2019-08-30 | — | — | CN | disclosed |
| CN-108586376-A | A method of iodo benzoxazine is prepared by cuprous iodide | 常州大学 | 2018-09-28 | — | — | CN | disclosed |