Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1465488 | 0.86 | SRD5A2 (0.45) | ALDH1A1RAB9AMEN1HPGDKMT2A | |
| SCHEMBL28327481 | 0.83 | NR3C2 (0.44) | NR3C2NPSR1ALDH1A1PTPN1SMN1; SMN2 | |
| SCHEMBL27911323 | 0.82 | KMT2A (0.50) | NR3C2ALDH1A1ALOX15PTPN1SMN1; SMN2 | |
| SCHEMBL1003807 | 0.80 | NPSR1 (0.61) | NR3C2NPSR1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6438589 | 0.80 | PTPN1 (0.49) | NPSR1ALDH1A1ALOX15PTPN1SMN1; SMN2 | |
| SCHEMBL8034169 | 0.80 | PTPN1 (0.50) | NPSR1ALDH1A1ALOX15LTB4R2PTPN1 | |
| SCHEMBL27894063 | 0.79 | TSHR (0.54) | ALDH1A1SMN1; SMN2RAB9AMEN1GAA | |
| SCHEMBL31393783 | 0.79 | NPSR1 (0.45) | NR3C2NPSR1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL15999740 | 0.79 | NR3C2 (0.49) | NR3C2NPSR1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL27541993 | 0.79 | NR3C2 (0.49) | NR3C2NPSR1ALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070031854-A1 | Novel 10,10'-substituted-9,9'-biacridilidine luminescent molecules their preparation and uses | KATSILOMETES GEORGE W | 2007-02-08 | — | — | US | disclosed |
| US-20020034828-A1 | NOVEL 10,10'-SUBSTITUTED-9,9'-BIACRIDINE LUMINESCENT MOLECULES AND THEIR PREPARATION | PIERCE CHEMICAL COMPANY | 2002-03-21 | — | — | US | disclosed |
| EP-1026156-A2 | Novel 10, 10'-substituted-9,9'-biacridine luminescent molecules and their preparation | PIERCE CHEMICAL COMPANY (US) | 2000-08-09 | — | — | EP | disclosed |
| US-5866335-A | Preparation of derivatized 10,10'-substituted-9,9'-biacridine luminescent molecules and signal solutions | Katsilometes, George W. (US) | 1999-02-02 | — | — | US | disclosed |