Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 4/20 | 0.39 |
| ▸ | ADH1A | P07327 | 4/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 3/20 | 0.37 |
| ▸ | ADH7 | P40394 | 2/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368356 | 0.82 | GRIN2B (0.56) | GRIN2BADH1BADH1AAKR1C3AKR1C1 | |
| SCHEMBL23130436 | 0.82 | GRIN2B (0.56) | GRIN2BADH1BADH1AAKR1C3AKR1C1 | |
| SCHEMBL28329005 | 0.81 | ADRB2 (0.44) | MAPTADH1BADH1AADH1CADH7 | |
| SCHEMBL14368359 | 0.81 | ADRB2 (0.44) | GRIN2BADH1BADH1ATRPV1ADH1C | |
| SCHEMBL25994722 | 0.79 | ADH1B (0.50) | GAAMAPTADH1BADH1AADH1C | |
| SCHEMBL25994590 | 0.79 | ADH1B (0.50) | GAAMAPTADH1BADH1AADH1C | |
| SCHEMBL25994810 | 0.78 | ESR1 (0.40) | MAPTALDH1A1 | |
| SCHEMBL20653843 | 0.77 | TRPV1 (0.48) | AKR1C3AKR1C1TRPV1 | |
| SCHEMBL16762030 | 0.72 | GAA (0.43) | GRIN2BGAAMAPTAKR1C3AKR1C1 | |
| SCHEMBL16761873 | 0.72 | GAA (0.43) | GRIN2BGAAMAPTAKR1C3AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110461838-A | oxadiazole transient receptor potential channel inhibitors | HOFFMANN LA ROCHE | 2019-11-15 | — | — | CN | disclosed |