Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.31 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28195323 | 0.87 | BRD4 (0.40) | CYP3A4ALDH5A1ABATBRD4CREBBP | |
| SCHEMBL27328290 | 0.75 | ALOX5 (0.43) | BRD4CREBBPMAPT | |
| SCHEMBL28152167 | 0.75 | TAAR1 (0.41) | MAPT | |
| SCHEMBL28151098 | 0.71 | GLA (0.33) | MAPT | |
| SCHEMBL28301796 | 0.70 | ERN1 (0.35) | — | |
| SCHEMBL27518193 | 0.70 | RPS6KA3 (0.31) | MAPT | |
| SCHEMBL27468059 | 0.68 | — | — | |
| SCHEMBL27855763 | 0.67 | GAA (0.30) | MAPT | |
| SCHEMBL292432 | 0.63 | PARP1 (0.60) | BRD4CREBBP | |
| SCHEMBL1079408 | 0.63 | ESR2 (0.41) | CYP3A4ALDH5A1ABATTYRESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110418790-A | Imidazo pyrroles's ketone compound as p53-MDM2 inhibitor | LUOXIN BIOTECHNOLOGY SHANGHAI CO LTD | 2019-11-05 | — | — | CN | disclosed |