SCHEMBL28328623

SCHEMBL28328623

CC1CCC(C(C)C)C(C(O)C(C)O)C1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 4/20 0.55
TRPA1 O75762 2/20 0.55
EPHX1 P07099 3/20 0.47
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.37
KCNA5 P22460 1/20 0.36
TRPV1 Q8NER1 3/20 0.36
KDM4E B2RXH2 1/20 0.35
APOBEC3A P31941 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
GAA P10253 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL1660899 0.93 EPHX1 (0.50) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL13465301 0.83 TRPM8 (0.65) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL4389935 0.83 TRPM8 (0.65) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL30604482 0.82 TRPM8 (0.62) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL1659675 0.81 TRPM8 (0.48) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL27708449 0.80 TRPM8 (0.52) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL31443265 0.78 TRPM8 (0.58) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL18420148 0.77 TRPM8 (0.52) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL5680423 0.76 TRPM8 (0.52) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL31148535 0.76 TRPM8 (0.52) TRPM8TRPA1EPHX1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111343963-B Use of physiologically cooling active ingredients and compositions comprising such active ingredients 巴斯夫欧洲公司 2023-09-12 CN disclosed
CN-110719768-B Powder comprising crystals having inclusions enclosed therein 西姆莱斯有限公司 2023-06-02 CN disclosed
CN-110719768-A Powder comprising crystals having inclusions encapsulated therein 西姆莱斯有限公司 2020-01-21 CN disclosed
CN-110461165-A Soft sweet LOTTE CO LTD 2019-11-15 CN disclosed