Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955520 | 0.83 | TDP1 (0.54) | TDP1TSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL1708882 | 0.82 | KDM4E (0.49) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| SCHEMBL31522017 | 0.81 | TDP1 (0.52) | TDP1TSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL28829625 | 0.81 | TDP1 (0.52) | TDP1TSHRLMNAHSD17B10ALDH1A1 | |
| Dimethyl Phthalate SCHEMBL28487305 | 0.79 | TDP1 (0.65) | TDP1TSHRLMNAHSD17B10ALDH1A1 | |
| Benzene SCHEMBL28449714 | 0.79 | TSHR (0.59) | TDP1TSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL63699 | 0.77 | TSHR (0.61) | TDP1TSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL7668655 | 0.77 | TDP1 (0.48) | TDP1TSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL6135987 | 0.76 | TSHR (0.52) | TDP1TSHRLMNAHSD17B10ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28953721 | 0.76 | TSHR (0.59) | TDP1TSHRLMNAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074800-B | substituted bicyclic heteroaryl compounds as RXR agonists | 康内克斯生命科学私人有限公司 | 2019-11-12 | — | — | CN | disclosed |