Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | ACR | P10323 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2441955 | 0.89 | SLC6A3 (0.65) | SLC6A3KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL13813927 | 0.82 | SLC6A3 (0.72) | SLC6A3KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL30114910 | 0.82 | HTT (0.71) | SLC6A3KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL6674467 | 0.82 | SLC6A3 (0.61) | SLC6A3KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL3842861 | 0.82 | ELANE (0.46) | KMT2AMEN1TSHRHSD17B10MAPT | |
| SCHEMBL63699 | 0.81 | TSHR (0.61) | SLC6A3KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL4386585 | 0.81 | SLC6A3 (0.56) | SLC6A3KMT2AMEN1TSHRHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28953721 | 0.80 | TSHR (0.59) | SLC6A3KMT2AMEN1TSHRHSD17B10 | |
| Benzene SCHEMBL28449714 | 0.80 | TSHR (0.59) | SLC6A3KMT2AMEN1TSHRHSD17B10 | |
| Fluoride SCHEMBL28310481 | 0.80 | TSHR (0.59) | SLC6A3KMT2AMEN1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074800-B | substituted bicyclic heteroaryl compounds as RXR agonists | 康内克斯生命科学私人有限公司 | 2019-11-12 | — | — | CN | disclosed |