Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28343059 | 0.86 | IDO1 (0.51) | KDM4EALDH1A1PTGDR2 | |
| SCHEMBL28328763 | 0.80 | CYP19A1 (0.48) | PTGDR2ADORA3 | |
| SCHEMBL28328678 | 0.80 | PTGER4 (0.54) | MEN1KMT2AALDH1A1PTGDR2ADORA3 | |
| SCHEMBL28329962 | 0.77 | PTGDR2 (0.41) | KDM4EPTGDR2 | |
| SCHEMBL28329954 | 0.76 | CNR2 (0.48) | ALDH1A1PTGDR2ATM | |
| SCHEMBL11166536 | 0.74 | PTGDR2 (0.49) | MEN1KMT2AKDM4EALDH1A1PTGDR2 | |
| SCHEMBL11094843 | 0.74 | PTGDR2 (0.52) | MEN1KMT2AKDM4EALDH1A1PTGDR2 | |
| SCHEMBL28329955 | 0.73 | PTGER4 (0.55) | MEN1KMT2AKDM4EALDH1A1PTGDR2 | |
| SCHEMBL28329963 | 0.73 | AKR1B1 (0.42) | KDM4EALDH1A1PTGDR2 | |
| SCHEMBL6581989 | 0.71 | TGM2 (0.51) | TGM2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110498773-B | Method for synthesizing 1, 4-substituted 1,2, 3-triazole from acetylenic acid | 乐山师范学院 | 2021-07-02 | — | — | CN | disclosed |
| CN-110526875-A | A kind of acetylenic acid multicomponent synthesis 1,4- replaces the method for 1,2,3- triazole | UNIV LESHAN NORMAL | 2019-12-03 | — | — | CN | disclosed |
| CN-110498772-A | A kind of Terminal Acetylenes multicomponent synthesis 1,4- replaces the method for 1,2,3- triazole | UNIV LESHAN NORMAL | 2019-11-26 | — | — | CN | disclosed |
| CN-110498773-A | A kind of acetylenic acid synthesis 1,4- replaces the method for 1,2,3- triazole | UNIV LESHAN NORMAL | 2019-11-26 | — | — | CN | disclosed |
| CN-106866557-B | (Z)-β-alkenyl bromine multicomponent prepares the method and application of 1,4- substitution -1,2,3- triazole | 乐山师范学院 | 2019-11-12 | — | — | CN | disclosed |