Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28878851 | 0.88 | KDM4E (0.53) | MAPTSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL28331427 | 0.88 | ALDH1A1 (0.51) | MAPTSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL28331435 | 0.87 | CMA1 (0.46) | MAPTSMN1; SMN2TSHRALDH1A1KMT2A | |
| SCHEMBL28331488 | 0.87 | MAPT (0.56) | MAPTSMN1; SMN2LMNATP53TSHR | |
| SCHEMBL28330152 | 0.84 | TRPV6 (0.52) | MAPTSMN1; SMN2TSHRALDH1A1KMT2A | |
| SCHEMBL28331553 | 0.84 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2LMNATP53TSHR | |
| SCHEMBL28330007 | 0.81 | CMA1 (0.53) | MAPTSMN1; SMN2LMNATP53TSHR | |
| SCHEMBL20379142 | 0.80 | SMN1; SMN2 (0.49) | MAPTSMN1; SMN2LMNATP53TSHR | |
| SCHEMBL28878859 | 0.78 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2LMNATP53TSHR | |
| SCHEMBL20379417 | 0.75 | SMN1; SMN2 (0.54) | MAPTSMN1; SMN2LMNATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110494136-A | Cytoprotective compounds and application thereof | ETH ZUERICH | 2019-11-22 | — | — | CN | claimed |
| CN-110494136-A | Cytoprotective compounds and application thereof | ETH ZUERICH | 2019-11-22 | — | — | CN | disclosed |