1,2-Naphthoquinone

1,2-Naphthoquinone

SCHEMBL28330150

CCCCCCl.O=C1C=Cc2ccccc2C1=O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
PTPN1 P18031 3/20 0.62
CES1 P23141 3/20 0.62
MEN1 O00255 2/20 0.62
MAPT P10636 2/20 0.62
KMT2A Q03164 2/20 0.62
PTPRC P08575 2/20 0.62
KDM4E B2RXH2 1/20 0.62
LMNA P02545 1/20 0.62
BCHE P06276 1/20 0.62
POLB P06746 1/20 0.62
THRB P10828 1/20 0.62
PKM P14618 1/20 0.62
IDO1 P14902 1/20 0.62
HPGD P15428 1/20 0.62
ALOX15 P16050 1/20 0.62
ACHE P22303 1/20 0.62
RECQL P46063 1/20 0.62
HSD17B10 Q99714 1/20 0.62
PTPN22 Q9Y2R2 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthoquinone SCHEMBL27826976 0.83 IDO1 (0.54) ALDH1A1PTPN1MEN1MAPTKMT2A
1,2-Naphthoquinone SCHEMBL27880767 0.83 PTPRC (0.83) ALDH1A1PTPN1CES1MEN1MAPT
Naphthoquinone SCHEMBL28845464 0.82 IDO1 (0.52) ALDH1A1PTPN1MEN1MAPTKMT2A
1,2-Naphthoquinone SCHEMBL27614106 0.80 PTPRC (0.77) ALDH1A1PTPN1CES1MEN1MAPT
SCHEMBL9513382 0.79 TSHR (0.52) ALDH1A1PTPN1LMNASETD7NPC1
1,2-Naphthoquinone SCHEMBL27880732 0.79 PTPRC (0.91) ALDH1A1PTPN1CES1MEN1MAPT
1,2-Naphthoquinone SCHEMBL173316 0.79 PTPRC (1.00) ALDH1A1PTPN1CES1MEN1MAPT
1,2-Naphthoquinone SCHEMBL15167712 0.79 PTPRC (1.00) ALDH1A1PTPN1CES1MEN1MAPT
1,2-Naphthoquinone SCHEMBL29363665 0.79 PTPRC (1.00) ALDH1A1PTPN1CES1MEN1MAPT
1,2-Naphthoquinone SCHEMBL30715501 0.77 PTPRC (0.95) ALDH1A1PTPN1CES1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107108795-B Fluorine-containing pyrolytic resin, anti-corrosion agent composition, color filter protecting layer composition, etchant resist and color filter protecting layer DIC株式会社 2019-11-05 CN disclosed