Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.49 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.49 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | F12 | P00748 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9405397 | 0.79 | NPC1 (0.49) | PI4KAPI4K2BPI4K2API4KBNPC1 | |
| SCHEMBL5638922 | 0.79 | NPC1 (0.49) | PI4KAPI4K2BPI4K2API4KBNPC1 | |
| SCHEMBL6260533 | 0.78 | GAA (0.47) | PI4KAPI4K2BPI4K2API4KBNCF1 | |
| SCHEMBL5494756 | 0.77 | KDM4E (0.37) | PI4KAPI4K2BPI4K2API4KBNCF1 | |
| SCHEMBL27659057 | 0.77 | P2RX4 (0.46) | PI4KAPI4K2BPI4K2API4KBNPC1 | |
| SCHEMBL4866386 | 0.77 | NPC1 (0.46) | PI4KAPI4K2BPI4K2API4KBNPC1 | |
| SCHEMBL28367072 | 0.76 | NPC1 (0.45) | PI4KAPI4K2BPI4K2API4KBNPC1 | |
| SCHEMBL27944468 | 0.76 | NPC1 (0.45) | PI4KAPI4K2BPI4K2API4KBNPC1 | |
| SCHEMBL17844100 | 0.75 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBNOS3 | |
| SCHEMBL31202561 | 0.74 | CYP2A6 (0.46) | PI4KAPI4K2BPI4K2API4KBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110476989-A | Application of the Kealiinine Alkaloid in prevention and treatment plant virus germ disease | UNIV NANKAI | 2019-11-22 | — | — | CN | disclosed |
| CN-110483405-A | Kealiinine analog derivative and its preparation and the application in Antiphytoviral and germ | UNIV NANKAI | 2019-11-22 | — | — | CN | disclosed |