SCHEMBL9405397

SCHEMBL9405397

Cc1nccn1-c1cccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.49
MAPK1 P28482 1/20 0.49
CYP2A6 P11509 3/20 0.45
CYP2E1 P05181 1/20 0.45
CYP3A4 P08684 1/20 0.45
HCAR1 Q9BXC0 2/20 0.42
PI4KA P42356 1/20 0.42
PI4K2B Q8TCG2 1/20 0.42
PI4K2A Q9BTU6 1/20 0.42
PI4KB Q9UBF8 1/20 0.42
BDKRB2 P30411 1/20 0.41
MAPT P10636 3/20 0.41
ATM Q13315 1/20 0.41
TP53 P04637 1/20 0.40
ALDH1A1 P00352 5/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
KMT2A Q03164 2/20 0.40
GSR P00390 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31202561 0.81 CYP2A6 (0.46) NPC1MAPK1CYP2A6CYP3A4HCAR1
SCHEMBL27659057 0.80 P2RX4 (0.46) NPC1MAPK1HCAR1PI4KAPI4K2B
SCHEMBL4866386 0.80 NPC1 (0.46) NPC1MAPK1CYP2A6HCAR1PI4KA
SCHEMBL5638922 0.79 NPC1 (0.49) NPC1MAPK1CYP2A6CYP3A4HCAR1
SCHEMBL28330184 0.79 PI4KA (0.49) NPC1MAPK1CYP2A6CYP3A4HCAR1
SCHEMBL14428964 0.78 CYP3A4 (0.50) CYP2A6CYP2E1CYP3A4HCAR1PI4KA
SCHEMBL26998342 0.78 NCF1 (0.46) CYP2A6CYP2E1CYP3A4MAPTATM
SCHEMBL27944468 0.76 NPC1 (0.45) NPC1MAPK1CYP3A4HCAR1PI4KA
SCHEMBL28367072 0.76 NPC1 (0.45) NPC1MAPK1CYP3A4HCAR1PI4KA
SCHEMBL8564307 0.75 NPC1 (0.42) NPC1MAPK1HCAR1PI4KAPI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101389487-B Optical recording medium and method for manufacturing the same RICOH KK 2010-09-08 CN disclosed
CN-101389487-A Optical recording medium and method for manufacturing the same RICOH KK (JP) 2009-03-18 CN disclosed
US-5310648-A Polymer-metal chelate compound CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1994-05-10 US disclosed
WO-1992013447-A1 TEMPLATE POLYMERIZATION USING METAL CHELATES AND FLUID IMPRINT MATRICES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-08-20 WO disclosed