Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27719924 | 0.88 | NPC1 (0.42) | NPC1MAPK1HTR2CHTR2APOLB | |
| SCHEMBL23017552 | 0.84 | HTR2C (0.40) | NPC1MAPK1HTR2CHTR2APOLB | |
| SCHEMBL19961723 | 0.84 | HTR2C (0.46) | NPC1HTR2CHTR2AKDM4ENISCH | |
| SCHEMBL27659057 | 0.84 | P2RX4 (0.46) | NPC1MAPK1PI4KAPI4K2BPI4K2A | |
| SCHEMBL27729314 | 0.80 | HTR2C (0.46) | HTR2CHTR2APOLBKDM4ENISCH | |
| SCHEMBL9405397 | 0.80 | NPC1 (0.49) | NPC1MAPK1HTR2CHTR2APOLB | |
| SCHEMBL5638922 | 0.77 | NPC1 (0.49) | NPC1MAPK1HTR2APOLBKDM4E | |
| SCHEMBL28330184 | 0.77 | PI4KA (0.49) | NPC1MAPK1HTR2APOLBKDM4E | |
| SCHEMBL5486071 | 0.77 | HTR2C (0.66) | MAPK1HTR2CHTR2AKDM4ENISCH | |
| SCHEMBL27944468 | 0.76 | NPC1 (0.45) | NPC1MAPK1HTR2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314701-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2008-01-01 | — | — | US | claimed |
| US-7314701-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2008-01-01 | — | — | US | disclosed |
| US-20050095527-A1 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2005-05-05 | — | — | US | disclosed |