Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | CSF1R | P07333 | 5/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14629344 | 0.85 | CDK5 (0.35) | L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL28264177 | 0.78 | BACE1 (0.37) | ABL1L3MBTL1HRH4HRH3NR3C1 | |
| Trifluoroacetic Acid SCHEMBL3278943 | 0.74 | HRH4 (0.35) | L3MBTL1HRH4HRH3DPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL28810979 | 0.73 | PDE3B (0.38) | L3MBTL1HRH4HRH3NR3C1PGR | |
| Trifluoroacetic Acid SCHEMBL29627038 | 0.72 | EGLN1 (0.36) | CYP2C9DPP4DPP7DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL28780341 | 0.70 | RIPK1 (0.40) | HRH4HRH3 | |
| SCHEMBL13386793 | 0.70 | MGAM (0.41) | CSF1RDPP4GSK3AGSK3B | |
| SCHEMBL29850702 | 0.68 | DAO (0.46) | — | |
| SCHEMBL2995033 | 0.68 | DAO (0.46) | — | |
| SCHEMBL29507860 | 0.68 | KDM4E (0.39) | CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372703-A | Five-ring heterocycles miazines compound and application thereof | 罗欣生物科技（上海）有限公司 | 2019-10-25 | — | — | CN | disclosed |