Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MB | P02144 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL861674 | 0.82 | SMN1; SMN2 (0.84) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL1176395 | 0.81 | TDP1 (0.65) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL6251431 | 0.79 | MAPT (0.48) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL11413359 | 0.76 | — | — | |
| SCHEMBL1203942 | 0.76 | SMN1; SMN2 (0.67) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL669782 | 0.76 | SMN1; SMN2 (0.67) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL11718858 | 0.76 | SMN1; SMN2 (0.67) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL3818831 | 0.75 | SMN1; SMN2 (1.00) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL11158565 | 0.75 | MAPT (0.83) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL3804765 | 0.75 | RAB9A (0.56) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483425-A | A kind of application of the acyl thiourea compound and preparation method thereof with anti-influenza A virus | UNIV WUHAN | 2019-11-22 | — | — | CN | disclosed |
| CN-110478344-A | A kind of acyl thiourea compound is preparing the application in anti-influenza B virus drug | UNIV WUHAN | 2019-11-22 | — | — | CN | disclosed |