Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28962436 | 0.78 | MAPK1 (0.55) | MAPTKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL28071724 | 0.77 | MAPK1 (0.53) | MAPTKDM4EGAAALDH1A1MAPK1 | |
| SCHEMBL28330820 | 0.75 | PTPN1 (0.56) | MAPTKDM4EGAAALDH1A1MAPK1 | |
| SCHEMBL8883107 | 0.74 | MAPK1 (0.44) | MAPTKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL8886599 | 0.74 | MAPK1 (0.49) | MAPTKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL28329591 | 0.73 | MAPK1 (0.41) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL28329589 | 0.73 | PTGS2 (0.47) | MAPTKDM4EGAAALDH1A1MAPK1 | |
| SCHEMBL4560752 | 0.73 | MAPK1 (0.52) | MAPTKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL29236914 | 0.70 | MEN1 (0.49) | MAPTKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL28878383 | 0.70 | DPP4 (0.43) | MAPTKDM4EALDH1A1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483571-A | (1- (substituted-phenyl) acenaphthylene base)-two (3,5- bis- (trifluoromethyl)) phenyl phosphine compound and preparation method thereof | UNIV SCIENCE & TECHNOLOGY CHINA | 2019-11-22 | — | — | CN | disclosed |