Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28962436 | 0.78 | MAPK1 (0.55) | MAPK1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL8886599 | 0.77 | MAPK1 (0.49) | MAPK1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL28330827 | 0.76 | GPR84 (0.42) | MAPK1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL28330820 | 0.75 | PTPN1 (0.56) | MAPK1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL28071724 | 0.74 | MAPK1 (0.53) | MAPK1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL8883107 | 0.74 | MAPK1 (0.44) | MAPK1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL28330822 | 0.73 | MAPT (0.50) | MAPK1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL28329589 | 0.73 | PTGS2 (0.47) | MAPK1MEN1MAPTKMT2ACA1 | |
| SCHEMBL9170583 | 0.73 | GABRA1 (0.52) | MAPK1MAPTCYP3A4CA1CA2 | |
| SCHEMBL4560752 | 0.73 | MAPK1 (0.52) | MAPK1MEN1MAPTKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483571-A | (1- (substituted-phenyl) acenaphthylene base)-two (3,5- bis- (trifluoromethyl)) phenyl phosphine compound and preparation method thereof | UNIV SCIENCE & TECHNOLOGY CHINA | 2019-11-22 | — | — | CN | disclosed |