Fluoride

Fluoride

SCHEMBL28332009

CCCCCCCCCC(N)CCCCCCCC.CCCCCCCCCCCCCCCCNCCCN.F

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 4/20 0.49
GNAI3 P08754 1/20 0.49
GNAO1 P09471 1/20 0.49
GNAI1 P63096 1/20 0.49
TSHR P16473 2/20 0.48
CA12 O43570 2/20 0.48
F13A1 P00488 2/20 0.48
CA2 P00918 2/20 0.48
CYP1A2 P05177 2/20 0.48
ALOX15 P16050 2/20 0.48
CA4 P22748 2/20 0.48
CA6 P23280 2/20 0.48
CA5A P35218 2/20 0.48
THPO P40225 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
CA5B Q9Y2D0 2/20 0.48
ALDH1A1 P00352 1/20 0.48
MEN1 O00255 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3628865 0.94 RELA (0.46) RELAGNAI3GNAO1GNAI1TSHR
SCHEMBL4169387 0.94 RELA (0.46) RELAGNAI3GNAO1GNAI1TSHR
SCHEMBL2123615 0.93 RELA (0.45) RELAGNAI3GNAO1GNAI1TSHR
SCHEMBL16429465 0.91 ALDH1A1 (0.50) RELAGNAI3GNAO1GNAI1TSHR
SCHEMBL22401552 0.89 ALDH1A1 (0.48) RELAGNAI3GNAO1GNAI1TSHR
SCHEMBL16247033 0.89 ALDH1A1 (0.48) RELAGNAI3GNAO1GNAI1TSHR
SCHEMBL17541814 0.89 ALDH1A1 (0.48) RELAGNAI3GNAO1GNAI1TSHR
SCHEMBL6429352 0.87 ALDH1A1 (0.50) RELAGNAI3GNAO1GNAI1TSHR
SCHEMBL11830992 0.87 ALDH1A1 (0.50) RELAGNAI3GNAO1GNAI1TSHR
SCHEMBL31563619 0.86 ALDH1A1 (0.54) GNAI3GNAO1GNAI1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110505864-A Polyphenol/PEG-based hydrogel system for dental paints DENTSPLY SIRONA INC 2019-11-26 CN claimed