Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28119120 | 0.83 | TSHR (0.35) | KDM1AADORA2AKCNH2 | |
| SCHEMBL8477471 | 0.80 | KDM1A (0.44) | KDM1AMAOAMAOBMPOBTK | |
| SCHEMBL248518 | 0.79 | KDM1A (0.41) | KDM1AMAOAMAOBMPOBTK | |
| SCHEMBL5924102 | 0.79 | SMN1; SMN2 (0.41) | KDM1AMAOAMAOBKCNH2 | |
| SCHEMBL27788777 | 0.79 | KCNH2 (0.36) | KDM1AMAOAMAOBKCNH2 | |
| Formic Acid Methyl Ester SCHEMBL31051630 | 0.78 | KDM1A (0.39) | KDM1AMAOAMAOBMPOBTK | |
| SCHEMBL4377728 | 0.77 | MPO (0.43) | KDM1AMAOAMAOBMPOBTK | |
| SCHEMBL13680832 | 0.76 | KDM1A (0.40) | KDM1AMAOAMAOBMPOBTK | |
| Formic Acid SCHEMBL29095784 | 0.76 | KDM1A (0.40) | KDM1AMAOAMAOBMPOBTK | |
| SCHEMBL1569730 | 0.76 | KDM1A (0.44) | KDM1AMAOAMAOBMPOBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890940-A | Synthetic method of 6-methoxy-2-picolinic acid | 嘉兴瑞驰生物科技有限公司 | 2022-08-12 | — | — | CN | claimed |
| CN-114890940-A | Synthetic method of 6-methoxy-2-picolinic acid | 嘉兴瑞驰生物科技有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114890940-A | Synthetic method of 6-methoxy-2-picolinic acid | 嘉兴瑞驰生物科技有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-110467601-A | A kind of pyrazoles bipyridyl ketone compounds, intermediate and preparation method and application | XIXI HOSPITAL OF HANGZHOU | 2019-11-19 | — | — | CN | disclosed |