Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248518 | 0.82 | KDM1A (0.41) | KDM1AMAOAMAOBLIPGTRPM5 | |
| SCHEMBL13680823 | 0.79 | TRPV3 (0.34) | KCNH2 | |
| SCHEMBL13680849 | 0.78 | SCN9A (0.43) | — | |
| SCHEMBL15677623 | 0.78 | KCNH2 (0.47) | KDM1AMAOAMAOBLIPGMPO | |
| SCHEMBL14626155 | 0.78 | KDM1A (0.48) | KDM1AMAOAMAOBLIPGTRPM5 | |
| SCHEMBL932468 | 0.77 | KDM1A (0.42) | KDM1AMAOAMAOBLIPGTRPM5 | |
| SCHEMBL1463893 | 0.77 | PARP1 (0.36) | KDM1AMAOAMAOBKCNH2 | |
| SCHEMBL6193822 | 0.77 | SMN1; SMN2 (0.45) | KDM1AMAOAMAOBMPOKCNH2 | |
| SCHEMBL2940008 | 0.77 | MPO (0.43) | KDM1AMAOAMAOBLIPGMPO | |
| SCHEMBL29792045 | 0.77 | MPO (0.43) | KDM1AMAOAMAOBLIPGMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |