Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28032572 | 1.00 | KMT2A (0.44) | KMT2AMEN1FNTAPGGT1BTACR1 | |
| SCHEMBL28032035 | 0.87 | MEN1 (0.44) | KMT2AMEN1ITGB1ITGA4MME | |
| SCHEMBL15947341 | 0.78 | TACR1 (0.43) | KMT2AMEN1FNTAPGGT1BTACR1 | |
| SCHEMBL27515952 | 0.76 | POLB (0.54) | TACR1TDP1ALDH1A1L3MBTL1GAA | |
| SCHEMBL8028858 | 0.73 | KMT2A (0.46) | KMT2AMEN1TDP1MTNR1AKDM4E | |
| SCHEMBL28032573 | 0.72 | MAPT (0.42) | KMT2AMEN1ITGB1ITGA4TDP1 | |
| SCHEMBL28332900 | 0.72 | MAPT (0.42) | KMT2AMEN1ITGB1ITGA4TDP1 | |
| SCHEMBL19514720 | 0.71 | CTSS (0.56) | KMT2AMEN1PPARDPPARAITGB1 | |
| SCHEMBL19514694 | 0.71 | CTSS (0.56) | KMT2AMEN1PPARDPPARAITGB1 | |
| SCHEMBL19514698 | 0.71 | CTSS (0.56) | KMT2AMEN1PPARDPPARAITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106967213-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2019-11-05 | — | — | CN | disclosed |