Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28032573 | 1.00 | MAPT (0.42) | MAPTKDM4EALDH1A1HPGDKEAP1 | |
| SCHEMBL19514697 | 0.81 | ALDH1A1 (0.45) | MAPTKDM4EALDH1A1HPGDKEAP1 | |
| SCHEMBL19514723 | 0.81 | ALDH1A1 (0.45) | MAPTKDM4EALDH1A1HPGDKEAP1 | |
| SCHEMBL28032035 | 0.75 | MEN1 (0.44) | HPGDKMT2AMEN1ITGB1ITGA4 | |
| SCHEMBL28332899 | 0.72 | KMT2A (0.44) | MAPTKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL28032572 | 0.72 | KMT2A (0.44) | MAPTKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL4966326 | 0.71 | LMNA (0.48) | ALDH1A1HPGDL3MBTL1KMT2AMEN1 | |
| SCHEMBL434691 | 0.70 | ALDH1A1 (0.58) | MAPTKDM4EALDH1A1HPGDKEAP1 | |
| SCHEMBL7712114 | 0.70 | ALDH1A1 (0.58) | MAPTKDM4EALDH1A1HPGDKEAP1 | |
| SCHEMBL434690 | 0.70 | ALDH1A1 (0.58) | MAPTKDM4EALDH1A1HPGDKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106967213-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2019-11-05 | — | — | CN | disclosed |