Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.41 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 3/20 | 0.39 |
| ▸ | CCR9 | P51686 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28333015 | 0.79 | SYK (0.42) | MAPTSYKPARP1 | |
| SCHEMBL3576444 | 0.76 | GPR52 (0.50) | GPR52ROCK2AURKARPS6KB1AURKB | |
| SCHEMBL30450461 | 0.75 | PPARA (0.46) | MAPTDHODHRAB9AMAPK8MAPK10 | |
| SCHEMBL31026154 | 0.73 | SYK (0.49) | MAPTRAB9AMAPK10SYKPARP15 | |
| SCHEMBL31026156 | 0.73 | SYK (0.49) | MAPTRAB9AMAPK10SYKPARP15 | |
| SCHEMBL13407882 | 0.73 | CHEK1 (0.47) | MAPK8FFAR1FFAR4 | |
| SCHEMBL30468358 | 0.73 | CHEK1 (0.47) | MAPK8FFAR1FFAR4 | |
| SCHEMBL31417793 | 0.72 | FFAR4 (0.44) | ALKBH1FFAR1FFAR4 | |
| SCHEMBL1135417 | 0.72 | AURKA (0.48) | MAPTAURKARPS6KB1AURKBSYK | |
| SCHEMBL30175265 | 0.71 | LMNA (0.55) | MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520423-A | AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO | 2019-11-29 | — | — | CN | disclosed |