Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | FGR | P09769 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.42 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932597 | 0.89 | ADORA2A (0.50) | ALDH1A1ADORA2AFGRPIM1MAOA | |
| SCHEMBL6130217 | 0.85 | HSD17B10 (0.42) | ALDH1A1HSD17B10ADORA2AHPGDNPC1 | |
| SCHEMBL6130219 | 0.85 | HSD17B10 (0.42) | ALDH1A1HSD17B10ADORA2AHPGDNPC1 | |
| SCHEMBL8321808 | 0.83 | KMT2A (0.44) | ALDH1A1HSD17B10ADORA2AFGRPIM1 | |
| SCHEMBL25014 | 0.80 | HSD17B10 (0.50) | ALDH1A1HSD17B10ADORA2AFGRPIM1 | |
| SCHEMBL29546125 | 0.80 | HSD17B10 (0.50) | ALDH1A1HSD17B10ADORA2AFGRPIM1 | |
| SCHEMBL30158993 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HSD17B10ADORA2AMAOAHPGD | |
| SCHEMBL9678804 | 0.79 | CYP3A4 (0.54) | ALDH1A1HSD17B10ADORA2AFGRPIM1 | |
| SCHEMBL28203049 | 0.79 | CYP3A4 (0.54) | ALDH1A1HSD17B10ADORA2AFGRPIM1 | |
| SCHEMBL3793739 | 0.79 | CYP3A4 (0.54) | ALDH1A1HSD17B10ADORA2AMAOAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718722-B2 | Alkylthio- and aryl(heteroyl)thio-substituted p-phenylenediamines, their manufacture and their use in rubber | FLEXSYS AMERICA L.P. (US) | 2010-05-18 | — | — | US | disclosed |
| EP-1186595-B1 | Diaryl-p-phenylenediamine disulfides | GOODYEAR TIRE & RUBBER (US) | 2003-11-26 | — | — | EP | disclosed |
| US-6627686-B1 | Mixture with rubber; oxidation resistance; tires, rolls, conveyor belts, footwear | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-09-30 | — | — | US | disclosed |
| EP-1186595-A1 | Diaryl-p-phenylenediamine disulfides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-03-13 | — | — | EP | disclosed |
| EP-0700963-B1 | Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines | GOODYEAR TIRE & RUBBER (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5726248-A | ANTIOXIDANTS FOR DIENE POLYMERS WITH HIGH MOLECULAR WEIGHTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0700963-A1 | Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-03-13 | — | — | EP | disclosed |