SCHEMBL6932597

SCHEMBL6932597

Cc1ccccc1-c1c(N)ccc(N)c1-c1ccccc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 5/20 0.50
TDP1 Q9NUW8 2/20 0.50
CSNK1A1 P48729 2/20 0.50
CSNK1D P48730 2/20 0.50
CSNK1G1 Q9HCP0 2/20 0.50
CYP3A4 P08684 2/20 0.50
FGR P09769 1/20 0.50
PIM1 P11309 1/20 0.50
MAOA P21397 1/20 0.50
DYRK1A Q13627 1/20 0.50
HIPK2 Q9H2X6 1/20 0.50
HEXA P06865 1/20 0.46
HEXB P07686 1/20 0.46
DPP4 P27487 1/20 0.44
ALDH1A1 P00352 4/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
TSHR P16473 2/20 0.43
ACHE P22303 1/20 0.43
CD44 P16070 1/20 0.42
SMN1; SMN2 Q16637 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2833308 0.89 ALDH1A1 (0.45) ADORA2ATDP1CSNK1A1CSNK1DCSNK1G1
SCHEMBL9678804 0.88 CYP3A4 (0.54) ADORA2ATDP1CSNK1A1CSNK1DCSNK1G1
SCHEMBL3462071 0.84 CD44 (0.48) ADORA2ATDP1CSNK1A1CSNK1DCSNK1G1
SCHEMBL30714451 0.84 CD44 (0.48) ADORA2ATDP1CSNK1A1CSNK1DCSNK1G1
SCHEMBL4229766 0.83 CA12 (0.41) ADORA2ATDP1CSNK1A1CSNK1DCSNK1G1
SCHEMBL31054315 0.82 HEXA (0.47) ADORA2ATDP1CYP3A4HEXAHEXB
SCHEMBL22812540 0.82 ALDH1A1 (0.47) ADORA2ATDP1CSNK1A1CSNK1DCSNK1G1
SCHEMBL1133067 0.81 MYC (0.56) TDP1CYP3A4HEXAHEXBALDH1A1
SCHEMBL6930545 0.81 DPP4 (0.46) ADORA2ATDP1CSNK1A1CSNK1DCSNK1G1
SCHEMBL2875165 0.81 ADORA2A (0.62) ADORA2ATDP1CSNK1A1CSNK1DCSNK1G1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110156607-A A kind of preparation method of tire anti-aging agent 3100 扬州市业昌助剂有限公司 2019-08-23 CN disclosed
EP-3507331-A1 A LIQUID ANTIOXIDANT COMPOSITION FOR RAW RUBBERS BASF SE (DE) 2019-07-10 EP disclosed
WO-2018041649-A1 A LIQUID ANTIOXIDANT COMPOSITION FOR RAW RUBBERS BASF SE (DE) 2018-03-08 WO disclosed
EP-1186595-B1 Diaryl-p-phenylenediamine disulfides GOODYEAR TIRE & RUBBER (US) 2003-11-26 EP disclosed
US-6627686-B1 Mixture with rubber; oxidation resistance; tires, rolls, conveyor belts, footwear THE GOODYEAR TIRE & RUBBER COMPANY 2003-09-30 US disclosed
EP-1186595-A1 Diaryl-p-phenylenediamine disulfides THE GOODYEAR TIRE & RUBBER COMPANY (US) 2002-03-13 EP disclosed
EP-0700963-B1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1999-04-14 EP disclosed
US-5726248-A ANTIOXIDANTS FOR DIENE POLYMERS WITH HIGH MOLECULAR WEIGHTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-03-10 US disclosed
EP-0700963-A1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-03-13 EP disclosed