Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28333027 | 0.98 | RIPK1 (0.46) | FAAHCNR1CNR2MCHR1RIPK1 | |
| SCHEMBL15053689 | 0.92 | RIPK1 (0.53) | FAAHCNR1CNR2MCHR1RIPK1 | |
| Hydrochloric Acid SCHEMBL28718671 | 0.90 | RIPK1 (0.51) | FAAHCNR1CNR2RIPK1APP | |
| SCHEMBL28331543 | 0.81 | CYP19A1 (0.45) | FAAHCNR1CNR2MCHR1HTR2C | |
| SCHEMBL28331549 | 0.80 | HTR2C (0.45) | MCHR1HTR2CCYP19A1 | |
| SCHEMBL22957805 | 0.78 | RIPK1 (0.54) | FAAHCNR1CNR2MCHR1RIPK1 | |
| SCHEMBL5673940 | 0.78 | ALDH1A1 (0.59) | FAAHCNR1CNR2MCHR1RIPK1 | |
| SCHEMBL22957766 | 0.76 | RIPK1 (0.55) | MCHR1RIPK1ALDH1A1HTR2C | |
| SCHEMBL24224814 | 0.76 | ALDH1A1 (0.61) | FAAHCNR1CNR2MCHR1RIPK1 | |
| SCHEMBL7318282 | 0.75 | RIPK1 (0.58) | FAAHCNR1CNR2MCHR1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520423-A | AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO | 2019-11-29 | — | — | CN | disclosed |