Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.38 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.38 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PGD | P52209 | 2/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL5181889 | 0.88 | PGD (0.44) | LPAR5LPAR1LPAR4LPAR2LPAR3 | |
| Monoethanolamine SCHEMBL29242756 | 0.87 | PGD (0.43) | LPAR5LPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL30277794 | 0.82 | PLA2G2C (0.41) | LPAR5SMN1; SMN2 | |
| Alcohol SCHEMBL28123008 | 0.81 | LPAR5 (0.51) | LPAR5LPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL14278848 | 0.79 | PGK1 (0.52) | LPAR5LPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL7341 | 0.79 | PGK1 (0.52) | LPAR5LPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL7340 | 0.79 | PGK1 (0.52) | LPAR5LPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL14278847 | 0.79 | PGK1 (0.52) | LPAR5LPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL6655023 | 0.79 | PGK1 (0.52) | LPAR5LPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL213379 | 0.79 | PGK1 (0.52) | LPAR5LPAR1LPAR4LPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110300749-A | Compound with somatostatin receptor agonistic activity and medical application thereof | 小野药品工业株式会社 | 2019-10-01 | — | — | CN | disclosed |