SCHEMBL28333342

SCHEMBL28333342

OB(O)C(F)(F)F.c1cc2ccc1-2

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 7/20 0.42
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
MGLL Q99685 2/20 0.38
ESR1 P03372 2/20 0.37
ESR2 Q92731 1/20 0.37
ORAI1 Q96D31 1/20 0.36
ORAI2 Q96SN7 1/20 0.36
ORAI3 Q9BRQ5 1/20 0.36
TRPV6 Q9H1D0 1/20 0.36
PTPN5 P54829 1/20 0.34
RXRA P19793 3/20 0.33
RXRB P28702 3/20 0.33
RXRG P48443 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3992915 0.78
Lithium SCHEMBL3759407 0.73
Boric Acid SCHEMBL1736251 0.73 ESR1 (0.50) CA1CA2MGLLESR1ESR2
SCHEMBL28526561 0.73 CA1 (0.38) KIF11CA1CA2MGLLESR1
Boric Acid SCHEMBL28549126 0.70 ESR1 (0.47) CA1CA2MGLLESR1ESR2
Boric Acid SCHEMBL2687058 0.70 ESR1 (0.47) CA1CA2MGLLESR1ESR2
SCHEMBL6607384 0.66 MGLL (0.86) KIF11CA1CA2MGLLORAI1
Trifluoroacetic Acid SCHEMBL29009901 0.65 CYP2C9 (0.46) KIF11PTPN5RXRARXRBRXRG
SCHEMBL30589936 0.63 ALDH1A1 (0.55) CA2ESR1ESR2
SCHEMBL30135412 0.63 ALDH1A1 (0.55) CA2ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107739374-B Organic solar cell receptor material and preparation method thereof 武汉工程大学 2019-12-17 CN claimed