Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31586332 | 1.00 | TRPA1 (0.50) | TRPA1PARP1CA1CA2MAOA | |
| SCHEMBL27986120 | 0.86 | PARP1 (0.41) | TRPA1PARP1CA1CA2MAOA | |
| Monoethanolamine SCHEMBL9090837 | 0.83 | HTR2A (0.42) | TRPA1PARP1CA1CA2MAOA | |
| SCHEMBL10546234 | 0.82 | CA1 (0.42) | TRPA1PARP1CA1CA2MAOA | |
| SCHEMBL23581855 | 0.82 | PARP1 (0.39) | TRPA1PARP1CA1CA2MAOA | |
| SCHEMBL23581856 | 0.82 | PARP1 (0.39) | TRPA1PARP1CA1CA2MAOA | |
| SCHEMBL8681237 | 0.82 | PARP1 (0.39) | TRPA1PARP1CA1CA2MAOA | |
| SCHEMBL461295 | 0.82 | GSK3A (0.46) | TRPA1PARP1CA1CA2MAOA | |
| SCHEMBL2161394 | 0.82 | PARP1 (0.39) | TRPA1PARP1CA1CA2MAOA | |
| SCHEMBL8681224 | 0.82 | PARP1 (0.39) | TRPA1PARP1CA1CA2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024091675-A1 | HIGH TEMPERATURE DIELECTRIC POLYMERS AND FILMS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-05-02 | — | — | WO | claimed |
| WO-2024091684-A1 | POLYSULFATE AND POLYSULFONATE POLYMERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-05-02 | — | — | WO | claimed |
| CN-114674945-A | Quality detection method for cyclobenzaprine hydrochloride | 正大制药（青岛）有限公司 | 2022-06-28 | — | — | CN | claimed |
| CN-110003024-B | Organic hole transport material containing spirodi (dibenzosuberene) and preparation method and application thereof | 中节能万润股份有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-110655504-B | Compound with dibenzosuberene as core and application thereof in organic electroluminescent device | 江苏三月科技股份有限公司 | 2022-01-04 | — | — | CN | claimed |
| CN-107602397-B | Compound with dibenzosuberene as core and application thereof | 中节能万润股份有限公司 | 2020-10-30 | — | — | CN | claimed |
| CN-107501052-B | Synthesis method of dimethoxy dibenzosuberene | 河南工程学院 | 2020-09-18 | — | — | CN | claimed |
| CN-107216279-B | Compound with dibenzosuberene as core and application thereof in organic electroluminescent device | 中节能万润股份有限公司 | 2020-07-17 | — | — | CN | claimed |
| EP-3668718-A1 | TAMPER-EVIDENT MATERIALS, ADHESIVES, SEALS, AND CONTAINERS | Sun Chemical Corporation (US) | 2020-06-24 | — | — | EP | claimed |
| CN-110655498-A | Compound with dibenzosuberene as central skeleton and application thereof | 江苏三月光电科技有限公司 | 2020-01-07 | — | — | CN | claimed |
| EP-0073845-B1 | IMIDAZOPYRIDINE-SPIRO-PIPERIDINE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1985-05-29 | — | — | EP | claimed |
| EP-0031561-B1 | A RECTALLY ADMINISTERED SUPPOSITORY COMPRISING A DRUG AND AN ADJUVANT | MERCK & CO. INC. (US) | 1985-04-10 | — | — | EP | claimed |
| US-4410716-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIULCER AGENTS | TOA EIYO KAGAKU KOGYO CO. LTD. (JP) | 1983-10-18 | — | — | US | claimed |
| US-4249003-A | Process for polycyclic amines | AKTIEBOLAGET LEO (SE) | 1981-02-03 | — | — | US | claimed |
| US-4235820-A | Process for dibenzocycloheptene compounds | MERCK & CO., INC. (US) | 1980-11-25 | — | — | US | claimed |
| US-3988342-A | TRANQUILIZERS | MERCK & CO., INC. (US) | 1976-10-26 | — | — | US | claimed |
| US-3981877-A | APPETITE STIMULANTS | MERCK & CO., INC. (US) | 1976-09-21 | — | — | US | claimed |
| US-3975437-A | ANALGESIC, ANTIPYRETIC, ANTIINFLAMMATORY | RHONE-POULENC S.A. (FR) | 1976-08-17 | — | — | US | claimed |
| US-3950407-A | Process for preparing dibenzo[a,d]cycloheptenes | RIKER LABORATORIES, INCORPORATED (US) | 1976-04-13 | — | — | US | claimed |
| US-3933905-A | ANALGESIC, ANTIPYRETIC, ANTIINFLAMMATORY | RHONE-POULENC S.A. (FR) | 1976-01-20 | — | — | US | claimed |