Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | DRD3 | P35462 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15281998 | 0.92 | ALDH1A1 (0.69) | ALDH1A1DRD3MEN1KMT2AGAA | |
| SCHEMBL15282083 | 0.90 | ALDH1A1 (0.64) | ALDH1A1DRD3MEN1KMT2AGAA | |
| SCHEMBL21828810 | 0.89 | MEN1 (0.79) | ALDH1A1DRD3MEN1KMT2AGAA | |
| SCHEMBL17799172 | 0.88 | MEN1 (0.66) | ALDH1A1DRD3MEN1KMT2AGAA | |
| SCHEMBL29388444 | 0.88 | ALDH1A1 (1.00) | ALDH1A1DRD3MEN1KMT2AGAA | |
| SCHEMBL7809357 | 0.88 | ALDH1A1 (1.00) | ALDH1A1DRD3MEN1KMT2AGAA | |
| SCHEMBL10915570 | 0.87 | ALDH1A1 (0.80) | ALDH1A1DRD3MEN1KMT2AKDM4E | |
| SCHEMBL2856476 | 0.87 | ALDH1A1 (0.82) | ALDH1A1DRD3MEN1KMT2AGAA | |
| SCHEMBL11401745 | 0.86 | KMT2A (0.61) | ALDH1A1DRD3MEN1KMT2AGAA | |
| SCHEMBL30811902 | 0.86 | ALDH1A1 (0.68) | ALDH1A1DRD3MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563645-B | Quinolone compound and preparation method and application thereof | 山东省联合农药工业有限公司 | 2021-03-30 | — | — | CN | disclosed |
| CN-110563645-A | Novel quinolone compound and preparation method and application thereof | 山东省联合农药工业有限公司 | 2019-12-13 | — | — | CN | disclosed |