SCHEMBL28335219

SCHEMBL28335219

[PbH2].c1ccc2[nH]c(Cc3cc4ccccc4[nH]3)cc2c1

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.67
AHR P35869 2/20 0.61
HRH3 Q9Y5N1 2/20 0.61
MTNR1A P48039 1/20 0.57
MTNR1B P49286 1/20 0.57
CHRNA7 P36544 1/20 0.53
PCSK9 Q8NBP7 5/20 0.51
AOC3 Q16853 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28338445 0.98 LOXL2 (0.69) LOXL2AHRHRH3MTNR1AMTNR1B
SCHEMBL401081 0.98 LOXL2 (0.69) LOXL2AHRHRH3MTNR1AMTNR1B
SCHEMBL29403791 0.98 LOXL2 (0.69) LOXL2AHRHRH3MTNR1AMTNR1B
SCHEMBL7169246 0.93 LOXL2 (0.69) LOXL2AHRHRH3MTNR1AMTNR1B
SCHEMBL31059889 0.93 LOXL2 (0.69) LOXL2AHRHRH3MTNR1AMTNR1B
SCHEMBL6860219 0.89 LOXL2 (0.64) LOXL2AHRHRH3MTNR1AMTNR1B
SCHEMBL4434365 0.85 LOXL2 (0.60) LOXL2AHRHRH3MTNR1AMTNR1B
SCHEMBL73259 0.85 LOXL2 (0.60) LOXL2AHRHRH3MTNR1AMTNR1B
SCHEMBL3663173 0.85 LOXL2 (0.60) LOXL2AHRHRH3MTNR1AMTNR1B
SCHEMBL2261199 0.85 LOXL2 (0.60) LOXL2AHRHRH3MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110446505-A Combination therapy for treating skin disorders SKINTECH LIFE SCIENCE LTD 2019-11-12 CN disclosed