Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.56 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 8/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27502333 | 0.87 | SCN9A (0.57) | SCN9ASRRNPC1RAB9AMAPT | |
| SCHEMBL28628480 | 0.83 | SCN9A (0.54) | SCN9ASRRNPC1RAB9AMAPT | |
| SCHEMBL27438213 | 0.83 | SCN9A (0.54) | SCN9ASRRNPC1RAB9AMAPT | |
| SCHEMBL27669149 | 0.80 | SCN9A (0.51) | SCN9ASRRNPC1RAB9AMAPT | |
| SCHEMBL28029609 | 0.80 | SCN9A (0.56) | SCN9ASRRNPC1RAB9AMAPT | |
| SCHEMBL28529040 | 0.80 | SCN9A (0.53) | SCN9ASRRNPC1RAB9AMAPT | |
| SCHEMBL29060746 | 0.79 | CTSK (0.47) | SCN9ANPC1RAB9AMAPTATM | |
| SCHEMBL3712940 | 0.79 | PPARG (0.51) | SRRPPARGPPARAACECTRB1 | |
| SCHEMBL15311168 | 0.78 | CTSK (0.49) | SCN9ANPC1RAB9AMAPTATM | |
| SCHEMBL14716956 | 0.78 | CTSK (0.49) | SCN9ANPC1RAB9AMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085429-B | Aromatic heterocyclic derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2019-12-10 | — | — | CN | disclosed |