Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22570410 | 0.81 | NPSR1 (0.44) | POLBMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL28001086 | 0.79 | ALDH1A1 (0.45) | POLBMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL27903557 | 0.79 | TSHR (0.50) | POLBKMT2ATSHRALDH1A1CYP3A4 | |
| SCHEMBL20850055 | 0.78 | PDCD1 (0.53) | ALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL28542823 | 0.78 | NPSR1 (0.41) | POLBMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL11454677 | 0.78 | ALDH1A1 (0.44) | POLBMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL28750160 | 0.78 | ALDH1A1 (0.44) | POLBMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL7918978 | 0.76 | ALDH1A1 (0.41) | POLBMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL28421146 | 0.76 | SMN1; SMN2 (0.47) | POLBMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL27460841 | 0.76 | ALDH1A1 (0.56) | POLBTSHRALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551057-B | Chiral 3,3-disubstituted oxindole derivative and synthesis method and application thereof | 华东师范大学 | 2023-02-07 | — | — | CN | disclosed |
| CN-110551057-A | Chiral 3, 3-disubstituted oxindole derivative and synthesis method and application thereof | UNIV EAST CHINA NORMAL | 2019-12-10 | — | — | CN | disclosed |