Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15008845 | 0.94 | TYR (0.39) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL14842441 | 0.86 | TAAR1 (0.31) | — | |
| SCHEMBL463162 | 0.85 | TYR (0.43) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL7447639 | 0.84 | TYR (0.46) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL27297994 | 0.84 | TYR (0.46) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL27327339 | 0.84 | TYR (0.46) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL27298915 | 0.84 | TYR (0.46) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL27305337 | 0.84 | TYR (0.46) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL8038209 | 0.84 | TYR (0.46) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL677099 | 0.82 | LIPG (0.40) | TYRALOX5MEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143170-B | For treating the aromatic compounds of pulmonary fibrosis, liver fibrosis, fibrosis of skin and cardiac fibrosis being substituted | 普罗米蒂克医药SMT有限公司 | 2019-11-08 | — | — | CN | disclosed |