Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.51 |
| ▸ | PPARA | Q07869 | 6/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28337010 | 0.88 | PPARA (0.62) | ACHEPPARAPPARGMTNR1AMTNR1B | |
| SCHEMBL31539531 | 0.87 | CYP4F2 (0.54) | ACHEPPARAPPARGMTNR1AMTNR1B | |
| SCHEMBL1789805 | 0.87 | PPARA (0.56) | ACHEPPARAPPARGMTNR1AMTNR1B | |
| SCHEMBL7282839 | 0.87 | PPARA (0.54) | PPARAPPARGHDAC1HDAC6 | |
| SCHEMBL11201208 | 0.83 | PPARA (0.51) | ACHEPPARAPPARGMTNR1AMTNR1B | |
| SCHEMBL11201205 | 0.83 | ACHE (0.49) | ACHEPPARAPPARGMTNR1AMTNR1B | |
| SCHEMBL28593564 | 0.83 | ACHE (0.58) | ACHEPPARAPPARGMTNR1AMTNR1B | |
| SCHEMBL26153362 | 0.80 | ACHE (0.61) | ACHE | |
| SCHEMBL6670104 | 0.79 | ACHE (0.59) | ACHE | |
| SCHEMBL7285397 | 0.78 | ACHE (0.47) | ACHEPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |