SCHEMBL28337082

SCHEMBL28337082

C=C(C(=O)c1ccccc1)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.77
CES2 O00748 2/20 0.77
TDP1 Q9NUW8 1/20 0.56
POLB P06746 2/20 0.56
MAPK1 P28482 2/20 0.56
ALDH1A1 P00352 4/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
NPC1 O15118 1/20 0.53
MITF O75030 1/20 0.53
RAB9A P51151 1/20 0.53
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
SRD5A2 P31213 1/20 0.51
TSHR P16473 1/20 0.50
BCHE P06276 1/20 0.50
MAOB P27338 1/20 0.50
CYP1B1 Q16678 1/20 0.50
CRHBP P24387 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL762542 1.00 CES1 (0.77) CES1CES2TDP1POLBMAPK1
SCHEMBL1370034 0.87 CES1 (1.00) CES1CES2TDP1POLBMAPK1
Benzil SCHEMBL27888964 0.85 CES1 (0.96) CES1CES2TDP1POLBMAPK1
SCHEMBL10476789 0.83 CES2 (0.67) CES1CES2POLBMAPK1ALDH1A1
Cyanide SCHEMBL10981240 0.82 CES1 (0.89) CES1CES2TDP1POLBMAPK1
SCHEMBL819944 0.82 TDP1 (0.64) CES1CES2TDP1POLBMAPK1
SCHEMBL10887019 0.82 CES1 (0.69) CES1CES2TDP1POLBMAPK1
SCHEMBL761381 0.81 CES2 (0.65) CES1CES2TDP1POLBMAPK1
SCHEMBL5694669 0.81 MAOB (0.56) CES1CES2TDP1ALDH1A1MEN1
SCHEMBL5694665 0.81 MAOB (0.56) CES1CES2TDP1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110590742-B N1Long chain alkyl-N3Application of piperidine ethyl imidazole salt 枣庄学院 2022-02-01 CN disclosed
CN-110590742-A N1Long chain alkyl-N3Application of piperidine ethyl imidazole salt 枣庄学院 2019-12-20 CN disclosed