SCHEMBL28337091

SCHEMBL28337091

CC(C(=O)c1ccccc1)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.54
ALDH1A1 P00352 2/20 0.53
TSHR P16473 2/20 0.51
NPC1 O15118 1/20 0.46
GAA P10253 1/20 0.46
NFKB1 P19838 1/20 0.46
RAB9A P51151 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
POLB P06746 1/20 0.44
MAOB P27338 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2431833 0.85 CYP1A2 (0.63) CYP1A2ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL2431836 0.85 CYP1A2 (0.63) CYP1A2ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL7588542 0.83 CYP1A2 (0.57) CYP1A2ALDH1A1TSHRNPC1GAA
SCHEMBL27474823 0.83 ALDH1A1 (0.58) CYP1A2ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL3003307 0.81 ALDH1A1 (0.57) CYP1A2ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL974764 0.80 ALDH1A1 (0.55) CYP1A2ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL2413159 0.80 ALDH1A1 (0.55) CYP1A2ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL7733065 0.80 CYP1A2 (0.57) CYP1A2ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL11518980 0.80 ALDH1A1 (0.55) CYP1A2ALDH1A1TSHRGAASMN1; SMN2
SCHEMBL29688451 0.80 ALDH1A1 (0.55) CYP1A2ALDH1A1TSHRTDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110590742-B N1Long chain alkyl-N3Application of piperidine ethyl imidazole salt 枣庄学院 2022-02-01 CN disclosed
CN-110590742-A N1Long chain alkyl-N3Application of piperidine ethyl imidazole salt 枣庄学院 2019-12-20 CN disclosed