Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2431836 | 0.89 | CYP1A2 (0.63) | ALDH1A1CYP1A2TSHRHSD17B10TDP1 | |
| SCHEMBL2431833 | 0.89 | CYP1A2 (0.63) | ALDH1A1CYP1A2TSHRHSD17B10TDP1 | |
| SCHEMBL27474823 | 0.87 | ALDH1A1 (0.58) | ALDH1A1CYP1A2TSHRHSD17B10TDP1 | |
| SCHEMBL7733065 | 0.84 | CYP1A2 (0.57) | ALDH1A1CYP1A2TSHRHSD17B10TDP1 | |
| SCHEMBL974764 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP1A2TSHRHSD17B10TDP1 | |
| SCHEMBL1305446 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP1A2TSHRHSD17B10TDP1 | |
| SCHEMBL29688451 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP1A2TSHRHSD17B10TDP1 | |
| SCHEMBL2413159 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP1A2TSHRHSD17B10TDP1 | |
| SCHEMBL10546754 | 0.84 | ALDH1A1 (0.68) | ALDH1A1CYP1A2TSHRHSD17B10TDP1 | |
| SCHEMBL9276508 | 0.82 | ALDH1A1 (0.57) | ALDH1A1CYP1A2TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197938-A1 | Process for producing indole compoud | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
| US-20070083053-A1 | Process for producing indole compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-04-12 | — | — | US | disclosed |
| EP-1606268-A1 | HETEROCYCLIC KINASE INHIBITORS | Abbott Laboratories (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004076424-A1 | HETEROCYCLIC KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2004-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197938-A1 | Process for producing indole compoud | IDO1, IDO2, NOS2 | ALDH1A1 2357/4885CYP1A2 41/4885TSHR 1679/4885 |
| US-20070083053-A1 | Process for producing indole compound | IDO2, IDO1, TDO2 | ALDH1A1 2793/4885CYP1A2 31/4885TSHR 1763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.