SCHEMBL28337096

SCHEMBL28337096

CN(C)CCCc1cc(-c2ccncc2)ccn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
CYP3A4 P08684 3/20 0.43
CYP2D6 P10635 3/20 0.43
HTR1D P28221 2/20 0.43
HTR1B P28222 2/20 0.43
ALDH1A1 P00352 2/20 0.43
CYP1A2 P05177 1/20 0.43
HTR1A P08908 1/20 0.43
ALOX15 P16050 1/20 0.43
CYP2C19 P33261 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ROCK2 O75116 2/20 0.42
CDC7 O00311 1/20 0.42
MAP4K4 O95819 1/20 0.42
PIM1 P11309 1/20 0.42
PRKACA P17612 1/20 0.42
CDK2 P24941 1/20 0.42
GSK3B P49841 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
IRAK4 Q9NWZ3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28011986 0.79 CYP2D6 (0.49) MAPTCYP3A4CYP2D6ALDH1A1TDP1
SCHEMBL28012363 0.79 CYP2D6 (0.49) MAPTCYP3A4CYP2D6ALDH1A1TDP1
SCHEMBL28078531 0.79 CYP2D6 (0.49) MAPTCYP3A4CYP2D6ALDH1A1TDP1
SCHEMBL27913958 0.79 CYP2D6 (0.49) MAPTCYP3A4CYP2D6ALDH1A1TDP1
SCHEMBL28011947 0.79 CYP2D6 (0.49) MAPTCYP3A4CYP2D6ALDH1A1TDP1
SCHEMBL28684192 0.78 SREBF2 (0.50) MAPTCYP3A4CYP2D6ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL29242809 0.77 CYP2D6 (0.37) MAPTCYP3A4CYP2D6MAP4K4LMNA
SCHEMBL17300703 0.77 KCNH2 (0.46) CYP2D6HTR1DALDH1A1CYP1A2CYP2C19
Bromide SCHEMBL28659622 0.77 HRH1 (0.42) MAPTMAP4K4LMNA
SCHEMBL28292679 0.76 CYP2D6 (0.46) MAPTCYP3A4CYP2D6ALDH1A1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110444799-A Neutral aqueous phase system flow battery system CHINASALT JINTAN CO LTD 2019-11-12 CN disclosed