Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | SCN1A | P35498 | 1/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.67 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.67 |
| ▸ | GHSR | Q92847 | 1/20 | 0.67 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.67 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28339271 | 0.90 | ALDH1A1 (0.83) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL23722827 | 0.90 | KDM4E (0.82) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL28338284 | 0.89 | ALDH1A1 (0.78) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL28337133 | 0.88 | ALDH1A1 (0.76) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL28338286 | 0.88 | KDM4E (0.66) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL23722826 | 0.85 | HTT (0.59) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL28338291 | 0.85 | KDM4E (0.78) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL28339324 | 0.81 | MEN1 (0.68) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL23722877 | 0.81 | KDM4E (0.90) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL23722886 | 0.81 | ALDH1A1 (0.81) | ALDH1A1KDM4ELMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590660-B | Quinoline carboxamide compound, preparation method thereof and application of quinoline carboxamide compound in resisting enterovirus 71 | 武汉大学 | 2021-02-19 | — | — | CN | claimed |
| CN-110590660-A | Quinoline carboxamide compound, preparation method thereof and application of quinoline carboxamide compound in resisting enterovirus 71 | 武汉大学 | 2019-12-20 | — | — | CN | claimed |
| CN-110590660-B | Quinoline carboxamide compound, preparation method thereof and application of quinoline carboxamide compound in resisting enterovirus 71 | 武汉大学 | 2021-02-19 | — | — | CN | disclosed |
| CN-110590660-A | Quinoline carboxamide compound, preparation method thereof and application of quinoline carboxamide compound in resisting enterovirus 71 | 武汉大学 | 2019-12-20 | — | — | CN | disclosed |