Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | GAA | P10253 | 1/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.78 |
| ▸ | SCN1A | P35498 | 1/20 | 0.78 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.78 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.78 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | GHSR | Q92847 | 1/20 | 0.78 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.78 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 2/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28339271 | 0.95 | ALDH1A1 (0.83) | KDM4EALDH1A1ABCB11LMNACYP1A2 | |
| SCHEMBL28338284 | 0.92 | ALDH1A1 (0.78) | KDM4EALDH1A1ABCB11LMNACYP1A2 | |
| SCHEMBL28339274 | 0.91 | ALDH1A1 (0.90) | KDM4EALDH1A1ABCB11LMNACYP1A2 | |
| SCHEMBL28337133 | 0.91 | ALDH1A1 (0.76) | KDM4EALDH1A1ABCB11LMNACYP1A2 | |
| Dibucaine SCHEMBL29810833 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1ABCB11LMNACYP1A2 | |
| Dibucaine SCHEMBL34473 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1ABCB11LMNACYP1A2 | |
| Dibucaine SCHEMBL19555661 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1ABCB11LMNACYP1A2 | |
| Dibucaine SCHEMBL22688962 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1ABCB11LMNACYP1A2 | |
| Dibucaine SCHEMBL29555902 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1ABCB11LMNACYP1A2 | |
| Dibucaine SCHEMBL31303 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1ABCB11LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590660-B | Quinoline carboxamide compound, preparation method thereof and application of quinoline carboxamide compound in resisting enterovirus 71 | 武汉大学 | 2021-02-19 | — | — | CN | disclosed |
| CN-110590660-A | Quinoline carboxamide compound, preparation method thereof and application of quinoline carboxamide compound in resisting enterovirus 71 | 武汉大学 | 2019-12-20 | — | — | CN | disclosed |