Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 17/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGAV | P06756 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21314546 | 0.96 | FGFR4 (0.38) | FGFR4ITGB3ITGAVMEN1TSHR | |
| SCHEMBL23527756 | 0.93 | FGFR4 (0.36) | FGFR4ITGB3ITGAV | |
| SCHEMBL20141262 | 0.91 | FGFR4 (0.39) | FGFR4MEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL5649956 | 0.88 | FGFR4 (0.37) | FGFR4MEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL20517697 | 0.87 | NOTUM (0.41) | FGFR4 | |
| SCHEMBL21328960 | 0.86 | ITGAV (0.37) | FGFR4ITGB3ITGAVMEN1TSHR | |
| SCHEMBL28337154 | 0.85 | ITGAV (0.36) | FGFR4ITGB3ITGAV | |
| SCHEMBL28311247 | 0.85 | FGFR4 (0.35) | FGFR4ITGB3ITGAVMEN1TSHR | |
| SCHEMBL20025188 | 0.84 | MPO (0.37) | FGFR4ITGAV | |
| SCHEMBL31076000 | 0.84 | MPO (0.37) | FGFR4ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283977-A | Inhibitors of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110573499-B | Inhibitors of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-113354635-A | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-110573499-A | inhibitors of α v β 6 integrin | 莫菲克医疗股份有限公司 | 2019-12-13 | — | — | CN | disclosed |