Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27545482 | 0.79 | KMT2A (0.59) | KMT2ACA1CA2CA9HTT | |
| SCHEMBL775874 | 0.79 | KMT2A (0.63) | KMT2ACA1CA2CA9HTT | |
| SCHEMBL323791 | 0.78 | CA1 (0.58) | KMT2ACA1CA2CA9HTT | |
| SCHEMBL11969934 | 0.78 | KMT2A (0.57) | KMT2ACA1CA2CA9HTT | |
| SCHEMBL633239 | 0.77 | CA2 (0.53) | KMT2ACA1CA2CA9ALDH1A1 | |
| SCHEMBL30706304 | 0.77 | KMT2A (0.61) | KMT2ACA1CA2CA9HTT | |
| SCHEMBL9698692 | 0.77 | KMT2A (0.61) | KMT2ACA1CA2CA9HTT | |
| SCHEMBL27404113 | 0.77 | KMT2A (0.61) | KMT2ACA1CA2CA9HTT | |
| Methane SCHEMBL18489374 | 0.76 | CA2 (0.56) | KMT2ACA1CA2CA9LMNA | |
| SCHEMBL22688923 | 0.76 | CA2 (0.56) | KMT2ACA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110506057-A | ALPHA synuclein antibody and application thereof | SQUIBB BRISTOL MYERS COMPANY | 2019-11-26 | — | — | CN | disclosed |