SCHEMBL28337286

SCHEMBL28337286

CCC(C)(O)COC(N)=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.55
HSD17B10 Q99714 1/20 0.55
ALOX15 P16050 1/20 0.48
TSHR P16473 3/20 0.41
ADRA1A P35348 2/20 0.41
CYP3A4 P08684 1/20 0.41
NFKB1 P19838 1/20 0.41
RAB9A P51151 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CHRM1 P11229 3/20 0.35
CHRM2 P08172 2/20 0.35
CHRM4 P08173 2/20 0.35
CHRM5 P08912 2/20 0.35
CHRM3 P20309 2/20 0.35
CHRNB2 P17787 2/20 0.35
CHRNA4 P43681 2/20 0.35
HTR1A P08908 1/20 0.35
CYP2C19 P33261 1/20 0.35
CHRNA7 P36544 1/20 0.35
HMGCR P04035 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28621958 0.81 ALDH1A1 (0.43) LMNAHSD17B10ADRA1ACHRM1HMGCR
SCHEMBL222664 0.79 LMNA (0.57) LMNAHSD17B10ALOX15TSHRADRA1A
SCHEMBL11143156 0.78 LMNA (0.52) LMNAHSD17B10ALOX15TSHRADRA1A
SCHEMBL7354257 0.78
SCHEMBL4565173 0.77 LMNA (0.46) LMNAHSD17B10ALOX15TSHRADRA1A
SCHEMBL20104322 0.76 LMNA (0.54) LMNAHSD17B10ALOX15TSHRADRA1A
SCHEMBL15025708 0.76 LMNA (0.53) LMNAHSD17B10ALOX15TSHRADRA1A
SCHEMBL765348 0.75
SCHEMBL29728513 0.75 LMNA (0.58) LMNAHSD17B10ALOX15TSHRADRA1A
SCHEMBL28791811 0.75 LMNA (0.44) LMNAHSD17B10ALOX15TSHRADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110637015-A Farnesoin X receptor agonists and uses thereof 梅塔科林公司 2019-12-31 CN claimed