SCHEMBL28337336

SCHEMBL28337336

Cn1c(C(=O)Nc2cccc(Br)c2Cl)nc2c1CN(C(=O)O)C2

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 20/20 0.52
CD274 Q9NZQ7 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28339595 0.91 PDCD1 (0.59) PDCD1CD274
SCHEMBL30010102 0.91 PDCD1 (0.59) PDCD1CD274
SCHEMBL30740265 0.86 PDCD1 (0.48) PDCD1CD274
SCHEMBL20295572 0.86 PDCD1 (0.48) PDCD1CD274
SCHEMBL20293196 0.83 PDCD1 (0.74) PDCD1CD274
SCHEMBL28337325 0.83 PDCD1 (0.51) PDCD1CD274
SCHEMBL27036653 0.82 PDCD1 (0.51) PDCD1CD274
SCHEMBL27133653 0.82 PDCD1 (0.51) PDCD1CD274
SCHEMBL20329010 0.82 PDCD1 (0.59) PDCD1CD274
SCHEMBL20295866 0.81 PDCD1 (0.49) PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110582493-A Benzoxazole derivatives as immunomodulators 因赛特公司 2019-12-17 CN disclosed