SCHEMBL30010102

SCHEMBL30010102

Cn1c(C(=O)Nc2cccc(Br)c2Cl)nc2c1CCN(C(=O)O)C2

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 20/20 0.59
CD274 Q9NZQ7 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28339595 1.00 PDCD1 (0.59) PDCD1CD274
SCHEMBL28337336 0.91 PDCD1 (0.52) PDCD1CD274
SCHEMBL28339592 0.89 PDCD1 (0.58) PDCD1CD274
SCHEMBL20293196 0.89 PDCD1 (0.74) PDCD1CD274
SCHEMBL27133653 0.89 PDCD1 (0.51) PDCD1CD274
SCHEMBL27036653 0.89 PDCD1 (0.51) PDCD1CD274
SCHEMBL29812811 0.87 PDCD1 (0.54) PDCD1CD274
SCHEMBL20293591 0.87 PDCD1 (0.54) PDCD1CD274
SCHEMBL28963545 0.85 PDCD1 (0.52) PDCD1CD274
SCHEMBL20314451 0.85 PDCD1 (0.58) PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114698376-B Biphenyl compound as immunomodulator and preparation method and application thereof 深圳微芯生物科技股份有限公司 2022-10-18 CN disclosed