Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinimide SCHEMBL11381109 | 0.89 | CRBN (0.65) | CRBNMAPTFFAR3LCKFYN | |
| Bicarbonate SCHEMBL28617862 | 0.89 | CRBN (0.77) | CRBNMAPTOR51E2ALDH1A1FKBP5 | |
| Succinimide SCHEMBL30804677 | 0.89 | CRBN (0.65) | CRBNMAPTFFAR3LCKFYN | |
| Bicarbonate SCHEMBL28617859 | 0.89 | CRBN (0.77) | CRBNMAPTOR51E2ALDH1A1FKBP5 | |
| Oxalic Acid SCHEMBL30524294 | 0.86 | CRBN (0.72) | CRBNMAPTOR51E2ALDH1A1FKBP5 | |
| Methacrylic Acid SCHEMBL9722957 | 0.86 | CRBN (0.56) | CRBNMAPTOR51E2ALDH1A1FKBP5 | |
| Methyl Alcohol SCHEMBL28109851 | 0.86 | CRBN (0.81) | CRBNMAPTOR51E2ALDH1A1FKBP5 | |
| SCHEMBL26618 | 0.83 | — | — | |
| SCHEMBL5778743 | 0.83 | CRBN (1.00) | CRBNMAPTOR51E2ALDH1A1FKBP5 | |
| Benzene SCHEMBL27901053 | 0.80 | CRBN (0.81) | CRBNMAPTOR51E2ALDH1A1FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457344-A | Low molecular weight protein degradation agent and application thereof | 凯普托尔治疗学股份有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-115896099-A | Nucleic acid stabilizing reagents, kits and methods of use thereof | 伯克利之光生命科技公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-109311930-B | Nucleic acid stabilizing reagents, kits and methods of use thereof | 伯克利之光生命科技公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-110603057-A | Nanoparticles for delivery of chemopreventive agents | 俄亥俄州创新基金会 | 2019-12-20 | — | — | CN | disclosed |