Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28617862 | 1.00 | CRBN (0.77) | CRBNMAPTOR51E2ALDH1A1FKBP5 | |
| Oxalic Acid SCHEMBL30524294 | 0.92 | CRBN (0.72) | CRBNMAPTOR51E2ALDH1A1FKBP5 | |
| Acetic Acid SCHEMBL28337387 | 0.89 | CRBN (0.68) | CRBNMAPTOR51E2ALDH1A1FKBP5 | |
| Succinimide SCHEMBL6036901 | 0.88 | CRBN (0.73) | CRBNMAPTALDH1A1ITGB3ITGB1 | |
| Succinimide SCHEMBL434236 | 0.88 | CRBN (0.73) | CRBNMAPTALDH1A1ITGB3ITGB1 | |
| Succinimide SCHEMBL6717091 | 0.88 | CRBN (0.73) | CRBNMAPTALDH1A1ITGB3ITGB1 | |
| SCHEMBL26618 | 0.87 | — | — | |
| SCHEMBL5778743 | 0.87 | CRBN (1.00) | CRBNMAPTOR51E2ALDH1A1FKBP5 | |
| Methyl Alcohol SCHEMBL28109851 | 0.85 | CRBN (0.81) | CRBNMAPTOR51E2ALDH1A1FKBP5 | |
| Benzene SCHEMBL27901053 | 0.85 | CRBN (0.81) | CRBNMAPTOR51E2ALDH1A1FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195699-A | Detergent composition and washing method using same | 凯斯科技股份有限公司 | 2021-07-30 | — | — | CN | claimed |